Structure of PDB 8sli Chain A Binding Site BS02

Receptor Information
>8sli Chain A (length=894) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CKGEVNFKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLF
AMKSWLRDVLRKGLVKAAQSTGAWILTSAGLARHVGQAVRDHSLAVRVVA
IGMASLDRILHRQLLDGTPIHYPADLCPLDSNLSHFILVAELQLSLEKHI
SQQRTGSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILGGIADVLAA
LVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTV
YDFDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAKSEIFNG
DVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRLQQLYHS
VSPKSLLFELLERKHEEGRLPAFSLHEVSRVLKDFLHDACRGFYQWLPDL
SRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSH
LEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRNHSWSRTT
CLHLATEADAKAFFAHDGVQAFLTKIWWGDMATILRLLGAFTCPALIYTN
LISFSAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFSYVLLVDFRPPP
QGPSGSEVTLYFWVFTLVLEEIRQGFFTDTRLVKKFTLYVEDNWNKCDMV
AIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKI
IIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHLEWIFRRVLYRPYLQIF
GQIPLDEIDEARVLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVV
QGNADMFWKFQRYHLIVEYHGRPALAPPFILLSHLSLVLKQVFRPDPVDQ
KIITWETVQKENFLSTMEKRRRDSEEEVLRKTAHRVDLIAKYIG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8sli Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8sli Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Resolution4.9 Å
Binding residue
(original residue number in PDB)		Q784 N807 D810
Binding residue
(residue number reindexed from 1)		Q624 N645 D648
Annotation score4
External links