Structure of PDB 8skv Chain A Binding Site BS02

Receptor Information
>8skv Chain A (length=224) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CHPRLSLHRPALEDLLLGSEANLTCTLTGLRDASGVTFTWTPSSGKSAVQ
GPPERDLCGCYSVSSVLPGCAEPWNHGKTFTCTAAYPESKTPLTATLSKS
GNTFRPEVHLLPPPSEELALNELVTLTCLARGFSPKDVLVRWLQGSQELP
REKYLTWASRQEPSQGTTTFAVTSILRVAAEDWKKGDTFSCMVGHEALPL
AFTQKTIDRLAGKPTHVNVSVVMA
Ligand information
>8skv Chain b (length=29) Species: 404331 (Streptococcus pyogenes serotype M4) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DPQYRALMGENQDLRKREGQYQDKIEELE
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8skv The Structures of Secretory IgA in complex with Streptococcus pyogenes M4 and human CD89 provide insights on mucosal host-pathogen interactions
Resolution3.1 Å
Binding residue
(original residue number in PDB)
T447 D449 K454
Binding residue
(residue number reindexed from 1)
T206 D208 K213
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8skv, PDBe:8skv, PDBj:8skv
PDBsum8skv
PubMed37872175
UniProtP01876|IGHA1_HUMAN Immunoglobulin heavy constant alpha 1 (Gene Name=IGHA1)

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