Structure of PDB 8sjd Chain A Binding Site BS02

Receptor Information

>8sjd Chain A (length=478) Species: 7370 (Musca domestica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RELKTVSADCKKEAIEKCAQWVVRDCRPFSAVSGSGFIDMIKFFIKVGAE
YGEHVNVEELLPSPITLSRKVTSDAKEKKALISREIKSAVEKDGASATID
LWTDNYIKRNFLGVTLHYHENNELRDLILGLKSLDFERSTAENIYKKLKA
IFSQFNVEDLSSIKFVTDRGANVVKSLANNIRINCSSHLLSNVLENSFEE
TPELNMPILACKNIVKYFKKANLQHRLRSSLKSECPTRWNSTYTMLRSIL
DNWESVIQILSEAGETQRIVHINKSIIQTMVNILDGFERIFKELQTCSSP
SLCFVVPSILKVKEICSPDVGDVADIAKLKVNIIKNVRIIWEENLSIWHY
TAFFFYPPALHMQQEKVAQIKEFCLSKMEDLELINPVCPSDEFEFYRKEI
VILSEDFKVMEWWNLNSKKYPKLSKLALSLLSIPASSAASERTFSLAGNI
ITEKRNRIGQQTVDSLLFLNSFYKNFCK

Ligand information

>8sjd Chain G (length=55) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cttatctatgtggcttacgtttgcctgtggcttgttgaagttctctggtt
cacgc

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8sjd Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding.
Resolution	5.1 Å
Binding residue (original residue number in PDB)	L181 W182 T183 R218 S219 T220 A221 A251 N252 K255 R318 W319
Binding residue (residue number reindexed from 1)	L101 W102 T103 R138 S139 T140 A141 A171 N172 K175 R238 W239

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0046872	metal ion binding
GO:0046983	protein dimerization activity

	Biological Process
GO:0006357	regulation of transcription by RNA polymerase II

	Cellular Component
GO:0005634	nucleus

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8sjd, PDBe:8sjd, PDBj:8sjd
PDBsum	8sjd
PubMed	37491363
UniProt	Q25438

[Back to BioLiP]