Structure of PDB 8sbm Chain A Binding Site BS02

Receptor Information
>8sbm Chain A (length=121) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTRLRQRIDAAVAQFADSGLRTSVQFVGPLSVVDSALADQAEAVVREAVS
NAVRHAKASTLTVRVKVDDDLCIEVTDNGRGLPDEFTGSGLTNLRQRAEQ
AGGEFTLASGTVLRWSAPLSQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8sbm Chain A Residue 606 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8sbm Understanding ATP Binding to DosS Catalytic Domain with a Short ATP-Lid.
Resolution1.47 Å
Binding residue
(original residue number in PDB)		D520 D522 C524
Binding residue
(residue number reindexed from 1)		D68 D70 C72
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
External links
PDB RCSB:8sbm, PDBe:8sbm, PDBj:8sbm
PDBsum8sbm
PubMed37905955
UniProtP9WGK3|DEVS_MYCTU Oxygen sensor histidine kinase response regulator DevS/DosS (Gene Name=devS)

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