Structure of PDB 8rqc Chain A Binding Site BS02

Receptor Information
>8rqc Chain A (length=300) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEEFRTLHDDDSIQVIPVLPQVMMILVPGQTLPLQLFHPQEVSMVRNLIQ
NDRTFAVLAYSNVQEAEFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKV
LELRTQSDGIQQAKVQILPEGSGDAETLMDRIKKQLREWDENLKDDSLPS
NPIDFSYWVAANLPIDDSLRIQLLKIDSAIQRLRCELDIMNKCTSLCCKQ
CQETEITTKNEIFSLSREGPMAAYVNPHGYVHEILTVYKACNLNLIGRPS
TEHSWFPGYAWTVAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALIPT
Ligand information
>8rqc Chain E (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PFQCNQCGASFTQKGNLLRHIKLHSGE
Receptor-Ligand Complex Structure
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PDB8rqc Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
Resolution2.15 Å
Binding residue
(original residue number in PDB)		C326 Q327 E328
Binding residue
(residue number reindexed from 1)		C201 Q202 E203
External links
PDB RCSB:8rqc, PDBe:8rqc, PDBj:8rqc
PDBsum8rqc
PubMed
UniProtQ96SW2|CRBN_HUMAN Protein cereblon (Gene Name=CRBN)

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