Structure of PDB 8rn5 Chain A Binding Site BS02

Receptor Information
>8rn5 Chain A (length=705) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDTFITRNFQTTIIQKAKNTMAEFSEDPELQPAMLFNICVHLEVCYVISD
MNFLDEEGKAYTRPQYEVIEGMPRTIAWMVQRSLAQEHGIETPKYLADLF
DYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSNESS
LDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEDVEKGIDFKLGQTISRL
RDISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLTWED
LRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECLE
KYSTLRDQTDPILIMKSEKANENFLWKLWRDCVNTISNEEMSNELQKTNY
AKWATGDGLTYQKIMKEVAIDDETMCQEEPKIPNKCRVAAWVQTEMNLLS
TLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLF
HTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLRGDT
DVVTVVTFEFSSTDPRVDSGKWPKYTVFRIGSLFVSGREKSVYLYCRVNG
TNKIQMKWGMEARRCLLQSMQQMEAIVEQESSIQGYDMTKACFKGDRVNS
PKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRL
LLLIQALKDRKGPWVFDLEGMYSGIEECISNNPWVIQSAYWFNEWLGFEK
EGSKV
Ligand information
>8rn5 Chain E (length=29) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TNYAKWATGDGLTYQKIMKEVAIDDETMC
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rn5 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Resolution2.88 Å
Binding residue
(original residue number in PDB)		N332 N334 F335 K338 Y361 W364 I375 M376 E378 V379 D382
Binding residue
(residue number reindexed from 1)		N321 N323 F324 K327 Y350 W353 I364 M365 E367 V368 D371
External links