Structure of PDB 8r5v Chain A Binding Site BS02

Receptor Information
>8r5v Chain A (length=122) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETAAAKFERQHMDSSTSASSNYCNQMMKSRNLTKDRCKPVNTFVHESLA
DVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTTQA
NKHIIVACEGNPYVPVHFDASV
Ligand information
Ligand IDTF4
InChIInChI=1S/C2H2Cl2O2/c3-1(4)2(5)6/h1H,(H,5,6)
InChIKeyJXTHNDFMNIQAHM-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04ClC(Cl)C(=O)O
OpenEye OEToolkits 1.5.0C(C(=O)O)(Cl)Cl
CACTVS 3.341OC(=O)C(Cl)Cl
FormulaC2 H2 Cl2 O2
NameDICHLORO-ACETIC ACID
ChEMBLCHEMBL13960
DrugBankDB08809
ZINCZINC000003830689
PDB chain8r5v Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8r5v Synthesis of P-stereodefined morpholino dinucleoside-3',6'-thiophosphoramidates using unexpected activator.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		Q37 H38 H145
Binding residue
(residue number reindexed from 1)		Q11 H12 H117
Annotation score1
Enzymatic activity
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8r5v, PDBe:8r5v, PDBj:8r5v
PDBsum8r5v
PubMed
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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