Structure of PDB 8qzi Chain A Binding Site BS02

Receptor Information
>8qzi Chain A (length=225) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEF
ITVRHCARIALDQLGVPPAPILKGDKGEPCWPDGMVGSLTHCAGYRGAVV
GRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRIL
FCAKEATYKAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTL
SGPPLTTLRGRWSVERGLVLTAIVL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8qzi Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qzi Catalytic Cycle of Type II 4'-Phosphopantetheinyl Transferases
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D114 E116 E157
Binding residue
(residue number reindexed from 1)		D112 E114 E155
Annotation score1
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008897 holo-[acyl-carrier-protein] synthase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009237 siderophore metabolic process
GO:0019290 siderophore biosynthetic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qzi, PDBe:8qzi, PDBj:8qzi
PDBsum8qzi
PubMed
UniProtO33336|PPTT_MYCTU 4'-phosphopantetheinyl transferase PptT (Gene Name=pptT)

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