Structure of PDB 8qtc Chain A Binding Site BS02

Receptor Information
>8qtc Chain A (length=238) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGREEFVYMAKLAEQAERYEEMVEFMEKVSAAVDGDELTVEERNLLSVAY
KNVIGARRASWRIISSIEQKEESRGNDDHVTAIREYRSKIETELSGICDG
ILKLLDSRLIPAAASGDSKVFYLKMKGDYHRYLAEFKTGQERKDAAEHTL
AAYKSAQDIANAELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAF
DEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQD
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain8qtc Chain A Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8qtc Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
D146 H150
Binding residue
(residue number reindexed from 1)
D144 H148
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0009742 brassinosteroid mediated signaling pathway
Cellular Component
GO:0000325 plant-type vacuole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8qtc, PDBe:8qtc, PDBj:8qtc
PDBsum8qtc
PubMed38783418
UniProtQ01525|14332_ARATH 14-3-3-like protein GF14 omega (Gene Name=GRF2)

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