Structure of PDB 8qg0 Chain A Binding Site BS02

Receptor Information
>8qg0 Chain A (length=427) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIA
LIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQV
DNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLT
FYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAM
VFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLT
LHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWV
MGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEI
VSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGI
IANVNRYGGYPINPEGNRSLQTNPWFL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qg0 The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Resolution3.43 Å
Binding residue
(original residue number in PDB)
N119 T120 Y123 K127 F138 I143 Y152 N155 L156 Q159 R189 N192 R257 K259 M260 L328 T341 P342 I343 K344 R380 R383 S384 R385 L427
Binding residue
(residue number reindexed from 1)
N119 T120 Y123 K127 F138 I143 Y152 N155 L156 Q159 R189 N192 R257 K259 M260 L328 T341 P342 I343 K344 R380 R383 S384 R385 L427
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8qg0, PDBe:8qg0, PDBj:8qg0
PDBsum8qg0
PubMed38197228
UniProtO28951|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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