Structure of PDB 8q75 Chain A Binding Site BS02

Receptor Information
>8q75 Chain A (length=774) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVNKVHLKLEGVSSPEDIKLIQSRLESVEGVNNVECDTAGQTIIVAYDPD
VTGPRLLIQCIQDAAQPPKYFNASLYSPPKQREAERHHEIRNYRNQFLWS
CLFSVPVFMFSMVLPMISPFGDWLFYKVCNNMTIGMLLRWLLCSPVQFII
GWRFYVGAYHALKRGYSNMDVLVALGTNAAYFYSVYIVLKALTSESFEGQ
DFFETSAMLISFILLGKYLEVVAKGKTSDALSKLTELAPETACLLTLDKD
GNAISETEISTQLLQRNDVIKIVPGEKVPVDGVVIKGQSHVNESMITGEA
RPIAKKPGDKVIGGTVNDNGCIIVKVTHVGSETALSQIVQLVEAAQLARA
PVQKLADRISRFFVPTVVVAAFLTWLGWFVAGQFDIYPREWIPKAMDSFE
LALQFGISVLVVACPCALGLATPTAVMVATGKGASQGVLIKGGNALEKAH
KVKAIIFDKTGTLTVGKPSVVQTKVFSKIPLLELCDLAAGAEANSEHPLS
KAIVEYTKKLREQYGSHSDHIMESKDFEVHPGAGVSANVEGKLVLVGNKR
LMQEFEVPISSEVEGHMSETEELARTCVLVAIDRTICGALSVSDPLKPEA
GRAISYLSSMGISSIMVTGDNWATAKSIAKEVGIGTVFAEIDPVGKAEKI
KDLQMKGLTVAMVGDGINDSPALAAADVGLAIGAGTDVAIEAADIVLMRS
SLEDVITAIDLSRKTLSRIRLNYVWALGYNVLGMPVAAGVLFPFTGIRLP
PWLAGACMAASSVSVVCSSLLLQL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8q75 Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q75 Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D641 T643 D848
Binding residue
(residue number reindexed from 1)		D458 T460 D665
Annotation score1
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0046872 metal ion binding
GO:0140581 P-type monovalent copper transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0035434 copper ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8q75, PDBe:8q75, PDBj:8q75
PDBsum8q75
PubMed38538615
UniProtQ6H7M3|HMA4_ORYSJ Copper-transporting ATPase HMA4 (Gene Name=HMA4)

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