Structure of PDB 8q42 Chain A Binding Site BS02

Receptor Information
>8q42 Chain A (length=434) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYA
KKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGG
TKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDTI
KIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKG
EDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDSSPIVKFNEKTP
QFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWF
EWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLI
GISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQK
DLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q42 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution1.97 Å
Binding residue
(original residue number in PDB)		G11 T12 N13 P16 S36 T47 T99 G101 T102 K103 Y128 A131 R132 E384 T409 G410
Binding residue
(residue number reindexed from 1)		G10 T11 N12 P15 S35 T46 T98 G100 T101 K102 Y127 A130 R131 E381 T406 G407
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q42, PDBe:8q42, PDBj:8q42
PDBsum8q42
PubMed38033326
UniProtE8URK0

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