Structure of PDB 8q41 Chain A Binding Site BS02

Receptor Information
>8q41 Chain A (length=427) Species: 509193 (Thermoanaerobacter brockii subsp. finnii Ako-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYAK
KLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGGT
KTMVVHIYNFLKEKFIKFEGSYLDARDYKLVYDYSEEAISLKDTIKIDIN
TLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFVK
WLEDPFRKIFKGENKLLEKTAKFKKHIEKLLSSPIVKFNEKTPQFIWDIL
NAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYSQ
IKSELLDRKLKEGEHFGISLKAQKKDSPYFALDIFLINGYQLIGISLTTS
STRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYETG
STQKRFVVFGIDDWADIGSKICEEVFK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8q41 Substrate selectivity and catalytic activation of the type III CRISPR-associated ancillary nuclease Can2
Resolution2.38 Å
Binding residue
(original residue number in PDB)		G11 T12 N13 P16 S36 T47 T99 G101 T102 K103 Y128 L129 A131 R132 E384 T409 G410
Binding residue
(residue number reindexed from 1)		G9 T10 N11 P14 S34 T45 T97 G99 T100 K101 Y122 L123 A125 R126 E374 T399 G400
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8q41, PDBe:8q41, PDBj:8q41
PDBsum8q41
PubMed38033326
UniProtE8URK0

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