Structure of PDB 8pvv Chain A Binding Site BS02

Receptor Information

>8pvv Chain A (length=427) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MMEYKIVENGLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIA
LIHNNQFSSLINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQV
DNAIDTGVDGIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLT
FYVDNLLVQFVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAM
VFKKDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLT
LHVSGKRPKMKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWV
MGDPNNRFHPYEGTKVKLSSKRYLLTLLQPYLKRNGLEMVTPIKPLSVEI
VSDNWTSEEYYHNVHEILDEIYYLSKMNWRGFRSRNLPVTVNYPKLVAGI
IANVNRYGGYPINPEGNRSLQTNPWFL

Ligand information

>8pvv Chain S (length=25) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gtttttccataggctccgccctcct

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8pvv The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Resolution	2.81 Å
Binding residue (original residue number in PDB)	I30 R147 F151 D154 N155 T188 R189 G255 H291 N293 T295 R322 K333 R334 R383
Binding residue (residue number reindexed from 1)	I30 R147 F151 D154 N155 T188 R189 G255 H291 N293 T295 R322 K333 R334 R383

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:8pvv, PDBe:8pvv, PDBj:8pvv
PDBsum	8pvv
PubMed	38197228
UniProt	O28951\|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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