Structure of PDB 8pi7 Chain A Binding Site BS02

Receptor Information
>8pi7 Chain A (length=168) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENLSPEEAAHQKAVVETLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGL
NQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGNRFKWGPA
SQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLV
TEVRVYNWFANRRKEEAF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8pi7 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		S142 H143 K155 K158 R203 F204 W206 R263 N270
Binding residue
(residue number reindexed from 1)		S53 H54 K66 K69 R94 F95 W97 R154 N161
External links
PDB RCSB:8pi7, PDBe:8pi7, PDBj:8pi7
PDBsum8pi7
PubMed38855865
UniProtP20823|HNF1A_HUMAN Hepatocyte nuclear factor 1-alpha (Gene Name=HNF1A)

[Back to BioLiP]