Structure of PDB 8pe3 Chain A Binding Site BS02

Receptor Information
>8pe3 Chain A (length=386) Species: 1308 (Streptococcus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GANAMGVLISAVGDTDPFRNFHDGALIHIARKYRPEKVILIFSEHTAKKQ
GNIEKALFSIAPNYEPELIIHDPIISDNEVHIFDVMFQRFSDILQEYYTK
EDEFILNLSSATPQIKSALFVINRLNGINVKAVQVSSPEHASNENIGHDN
DENIDELIEVNKDNKVNFIDRTIEDNAEKFSQALLKKTARDFIEKFDYKA
ALDILDQLSDFPNLKSVREEIRDVVNCLSKQDVPKGLRHKKLKEEEQKIL
SAYLTIELQRERGNVSESFIRIKNLTEFILEDYIKKRYPGLIDEYCEDYL
SLFDYSKLLKATKEFKLKRTIAPIIDMNSSRNKVAHSLSPLDSDAVKQLG
IAMKTLKTLVREQYHFSQSDFNFYQDLNKILLTKLN
Ligand information
Receptor-Ligand Complex Structure
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PDB8pe3 Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Resolution1.96 Å
Binding residue
(original residue number in PDB)		T11 R15 D19 S105 K112 V131 S132 S133 P134 H136 A137 S138 N139 R167
Binding residue
(residue number reindexed from 1)		T15 R19 D23 S109 K116 V135 S136 S137 P138 H140 A141 S142 N143 R171
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8pe3, PDBe:8pe3, PDBj:8pe3
PDBsum8pe3
PubMed37747760
UniProtA0A0A7HFE6|CSM6B_STRTR CRISPR system endoribonuclease Csm6' (Gene Name=csm6')

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