Structure of PDB 8pdp Chain A Binding Site BS02

Receptor Information
>8pdp Chain A (length=363) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSLQGIHLSDLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGE
ILYAKHADYKYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSL
GKIKNNKGEDLQMLDIHGVEKSWVEEIDKEARKTMATLLKESSIPQNQRP
SAPDTPIILLCVGALIFTKLASTIEVGLETTVRRANRVLSDALKRYPRMD
IPKIARSFYDLFEQKVYHRSLFIEYGKALGSSSTGSKAESLFVNIFMQAY
GAGQTMLRWGVIARSSNNIMLGHVSVQAELKQVTEVYDLVREMGPESGLL
HLRQSPKAGLLSLANCPNFASVVLGNASGLGIIGMYRGRVPNTELFSAAE
SYAKSLKESNKIN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pdp Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
K171 A173 S174 R185 R186 R189 G255 T257 W261 S314 Y338 R339
Binding residue
(residue number reindexed from 1)
K169 A171 S172 R183 R184 R187 G253 T255 W259 S312 Y336 R337
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Cellular Component
External links
PDB RCSB:8pdp, PDBe:8pdp, PDBj:8pdp
PDBsum8pdp
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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