Structure of PDB 8pdn Chain A Binding Site BS02

Receptor Information
>8pdn Chain A (length=339) Species: 694067 (Human metapneumovirus CAN97-83) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLSYKHAILKESQYTIKRDVGTTTAVTPSSLQQEITLLCGEILYAKHADY
KYAAEIGIQYISTALGSERVQQILRNSGSEVQVVLTRTYSQMLDIHGVEK
SWVEEIDKEARKTMATLLKESSGNIPQNQRPSAPDTPIILLCVGALIFTK
LASTIEVGLETTVRRANRVLSDALKRYPRMDIPKIARSFYDLFEQKVYHR
SLFIEYGKALGSSSTGSKAESLFVNIFMQAYGAGQTMLRWGVIARSSNNI
MLGHVSVQAELKQVTEVYDLVREMGPESGLLHLRQSPKAGLLSLANCPNF
ASVVLGNASGLGIIGMYRGRVPNTELFSAAESYAKSLKE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pdn Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus.
Resolution4.7 Å
Binding residue
(original residue number in PDB)
R186 R189 V190 S242 L243 N246
Binding residue
(residue number reindexed from 1)
R165 R168 V169 S221 L222 N225
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid
GO:0019029 helical viral capsid
GO:0030430 host cell cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pdn, PDBe:8pdn, PDBj:8pdn
PDBsum8pdn
PubMed37993464
UniProtQ6WBA1|NCAP_HMPVC Nucleoprotein (Gene Name=N)

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