Structure of PDB 8oxe Chain A Binding Site BS02

Receptor Information

>8oxe Chain A (length=302) Species: 4113 (Solanum tuberosum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RRYSVGYALAPKKQASFIQVSLVNLAKERGIDLIKIDTDKPLIDQGPFDC
VLHKMDGDDWKRQLKEYGSEFPQALIIDSPEAIERLHNRISMLQAVGEVE
IDCENASFGIPKQTVIYDAKMVSAINLENEGLEFPVIAKPLVADGSAKSH
KMLLVFNKDGLRKLKPPIVLQEFVNHGAVIFKVYVVGDYVKCVKRKSLPD
VKERLESYLPFSQVSNDDKYYKLMNLENAEYPPLSFLTNIARGLRRVTKL
HLFNFDVIRDDRVGNRYLIIDINYFPGYAKMPNYERVLTDFFWDVLNQND
KS

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8oxe Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8oxe Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1).
Resolution	2.26 Å
Binding residue (original residue number in PDB)	D44 D46
Binding residue (residue number reindexed from 1)	D37 D39
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.7.1.134: inositol-tetrakisphosphate 1-kinase.

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0005524	ATP binding
GO:0047325	inositol-3,4,5,6-tetrakisphosphate 1-kinase activity
GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity

	Biological Process
GO:0032957	inositol trisphosphate metabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:8oxe, PDBe:8oxe, PDBj:8oxe
PDBsum	8oxe
PubMed	38146842
UniProt	A4H2J0

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