Structure of PDB 8ol1 Chain A Binding Site BS02
Receptor Information
>8ol1 Chain A (length=98) Species:
9606
(Homo sapiens) [
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KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8ol1 Chain J (length=145) [
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caggatgtatatatctgacacgtgcctggagactagggagtaatcccctt
ggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctag
agctgtctacgaccaattgagcggcctcggcaccgggattctcca
Receptor-Ligand Complex Structure
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PDB
8ol1
Nuclear degradation of cGAS is essential for immune homeostasis
Resolution
3.5 Å
Binding residue
(original residue number in PDB)
R40 G44 R63 K64 L65 R69
Binding residue
(residue number reindexed from 1)
R4 G8 R27 K28 L29 R33
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:8ol1
,
PDBe:8ol1
,
PDBj:8ol1
PDBsum
8ol1
PubMed
38418882
UniProt
Q71DI3
|H32_HUMAN Histone H3.2 (Gene Name=H3C15)
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