Structure of PDB 8ofe Chain A Binding Site BS02

Receptor Information

>8ofe Chain A (length=164) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQ
VDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALV
PRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLK
QQRIRQKVEKLDRL

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

8ofe Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	8ofe Structural Insights into Antibacterial Payload Release from Gold Nanoparticles Bound to E. coli Peptide Deformylase.
Resolution	1.4 Å
Binding residue (original residue number in PDB)	C90 H132 H136
Binding residue (residue number reindexed from 1)	C90 H132 H136
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.5.1.88: peptide deformylase.

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0008198	ferrous iron binding
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0042586	peptide deformylase activity
GO:0043022	ribosome binding
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation
GO:0043686	co-translational protein modification

	Cellular Component
GO:0005829	cytosol

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Cellular Component

External links

PDB	RCSB:8ofe, PDBe:8ofe, PDBj:8ofe
PDBsum	8ofe
PubMed	38057137
UniProt	P0A6K3\|DEF_ECOLI Peptide deformylase (Gene Name=def)

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