Structure of PDB 8ka5 Chain A Binding Site BS02

Receptor Information
>8ka5 Chain A (length=297) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QSEPWTVLAHKKPQKDWKAYNPKTMRPPPLPEGTKCVKVMTWNVNGLRGL
LKFESFSALQLAQRENFDILCLQETKLQVKDVEEIKKTLIDGYDHSFWSC
SVSKLGYSGTAIISRIKPLSVRYGTGLSGHDTEGRIVTAEFDSFYLINTY
VPNSGDGLKRLSYRIEEWDRTLSNHIKELEKSKPVVLTGDLNCAHEEIDI
FNPAGNKRSAGFTIEERQSFGANLLDKGFVDTFRKQHPGVVGYTYWGYRH
GGRKTNKGWRLDYFLVSQSIAANVHDSYILPDINGSDHCPIGLILKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8ka5 Arabidopsis AP endonuclease APR complex with 20bp THF-containing DNA
Resolution2.8 Å
Binding residue
(original residue number in PDB)		E313 Y346 Y389
Binding residue
(residue number reindexed from 1)		E74 Y107 Y150
Enzymatic activity
Enzyme Commision number 3.1.11.2: exodeoxyribonuclease III.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8ka5, PDBe:8ka5, PDBj:8ka5
PDBsum8ka5
PubMed38503293
UniProtP45951|ARP_ARATH DNA-(apurinic or apyrimidinic site) endonuclease, chloroplastic (Gene Name=ARP)

[Back to BioLiP]