Structure of PDB 8k32 Chain A Binding Site BS02

Receptor Information

>8k32 Chain A (length=332) Species: 643648 (Syntrophothermus lipocalidus DSM 12680)

ARMYYDADANLDLLKGKTIAVIGYGSQGHAQAQNLHDSGLEVVVGLRKPE
DDFTTAEWNQVVADGLTPLPVDEAARAAQIIQILVPDDIQAKVYREKIEP
YLNEGDALGFSHGFNIHFGQIVPPPSVDVFMVAPKSPGHLVRRMYRQGVG
VPGLIAVHNDHTGKALETGLAYAKGIGCTRAGVIATTFKEETETDLFGEQ
CVLCGGVTELIKAGFDTLVEAGYQPEIAYFECLHELKLIVDLIYEGGIGL
MRYSVSDTAEYGDLTVGPRIINENTRAEMKKVLAAIQDGTFARELLLEFQ
VGRPVFSALRRKGQEHLIEKVGKELRAMMPWL

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8k32 Chain A Residue 408

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8k32 Structural bases of coenzyme specificity of thermophilic ketol-acid reductoisomerase
• Resolution: 2.12 Å
• Binding residue (original residue number in PDB): D196 E200
• Binding residue (residue number reindexed from 1): D195 E199
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0004455 ketol-acid reductoisomerase activity
• GO:0016491 oxidoreductase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0008652 amino acid biosynthetic process
• GO:0009082 branched-chain amino acid biosynthetic process
• GO:0009097 isoleucine biosynthetic process
• GO:0009099 L-valine biosynthetic process

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:8k32, PDBe:8k32, PDBj:8k32
• PDBsum: 8k32
• UniProt: D7CJ24