Structure of PDB 8jpw Chain A Binding Site BS02

Receptor Information
>8jpw Chain A (length=594) Species: 196112 (Streptomyces sp. X-119-6) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANEMTYEQLARELLLVGPAPTNEDLKLRYLDVLIDNGLNPPGPPKRILIV
GAGIAGLVAGDLLTRAGHDVTILEANANRVGGRIKTFHAKKGEPSPFADP
AQYAEAGAMRLPSFHPLTLALIDKLGLKRRLFFNVDIDPQTGNQDAPVPP
VFYKSFKDGKTWTNGAPSPEFKEPDKRNHTWIRTNREQVRRAQYATDPSS
INEGFHLTGCETRLTVSDMVNQALEPVRDYYSVKQDDGTRVNKPFKEWLA
GWADVVRDFDGYSMGRFLREYAEFSDEAVEAIGTIENMTSRLHLAFFHSF
LGRATYWEIEGGSRMLPETLAKDLRDQIVMGQRMVRLEYYDPGSLTGPGG
PAVAIQTVPEGATQTWTGDLAIVTIPFSSLRFVKVTPPFSYKKRRAVIET
HYDQATKVLLEFSRRWWEFTEADWKRELDAIAPGLYDYYQQWGEDDRPAT
NAYGGGSTTDNPNRFMYYPSHPVPGTQGGVVLAAYSWSDDAARWDSFDDA
ERYGYALENLQSVHGRRIEVFYTGAGQTQSWLRDPYACGEAAVYTPHQMT
AFHLDVVRPEGPVYFAGEHVSLKHAWIEGAVETAVRAAIAVNEA
Ligand information
Ligand IDAKG
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(=O)CCC(=O)O
OpenEye OEToolkits 1.7.6C(CC(=O)O)C(=O)C(=O)O
CACTVS 3.385OC(=O)CCC(=O)C(O)=O
FormulaC5 H6 O5
Name2-OXOGLUTARIC ACID
ChEMBLCHEMBL1686
DrugBankDB08845
ZINCZINC000001532519
PDB chain8jpw Chain A Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8jpw Development of a novel single-chain l-glutamate oxidase from Streptomyces sp. X-119-6 by inserting flexible linkers
Resolution2.66 Å
Binding residue
(original residue number in PDB)		M131 R132 Y570 A660
Binding residue
(residue number reindexed from 1)		M109 R110 Y485 A575
Annotation score5
Enzymatic activity
Enzyme Commision number 1.4.3.11: L-glutamate oxidase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:8jpw, PDBe:8jpw, PDBj:8jpw
PDBsum8jpw
PubMed37487431
UniProtQ8L3C7|LGOX_STRSQ L-glutamate oxidase precursor (Gene Name=lgoX)

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