Structure of PDB 8jgj Chain A Binding Site BS02

Receptor Information

>8jgj Chain A (length=684) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GVGTYDDFHTIDWVREKCKDRERHRRINSKKKESAWEMTKSLYDAWSGWL
VVTLTGLASGALAGLIDIAADWMTDLKEGICLSALWYNHEQCCWGSKCPQ
WKTWAELIIGQAEGPGSYIMNYIMYIFWALSFAFLAVSLVKVFAPYACGS
GIPEIKTILSGFIIRGYLGKWTLMIKTITLVLAVASGLSLGKEGPLVHVA
CCCGNIFSYLFPKYSTNEAKKREVLSAASAAGVSVAFGAPIGGVLFSLEE
VSYYFPLKTLWRSFFAALVAAFVLRSINPFGNSRLVLFYVEYHTPWYLFE
LFPFILLGVFGGLWGAFFIRANIAWCRRRKSTKFGKYPVLEVIIVAAITA
VIAFPNPYTRLNTSELIKELFTDCGPLESSSLCDYRIPDRPAGVGVYSAI
WQLCLALIFKIIMTVFTFGIKVPSGLFIPSMAIGAIAGRIVGIAVEQLAY
YHHDWFIFKEWCEVGADCITPGLYAMVGAAACLGGVTRMTVSLVVIVFEL
TGGLEYIVPLMAAVMTSKWVGDAFGREGIYEAHIRLNGYPFLDAKEEFTH
TTLAADVMRPRRSDPPLAVLTQDNMTVDDIENMINETSYNGFPVIMSKES
QRLVGFALRRDLTIAIESARKKVCFAQLKLRSILDMSPFTVTDHTPMEIV
VDIFRKLGLRQCLVTHNGRLLGIITKKDILRHMA

Ligand information

Ligand ID

InChI

InChI=1S/ClH/h1H/p-1

InChIKey

VEXZGXHMUGYJMC-UHFFFAOYSA-M

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Cl-]

Formula

Name

CHLORIDE ION

PDB chain

8jgj Chain A Residue 904 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8jgj Structural basis of adenine nucleotides regulation and neurodegenerative pathology in ClC-3 exchanger.
Resolution	3.3 Å
Binding residue (original residue number in PDB)	S239 Y630
Binding residue (residue number reindexed from 1)	S150 Y530
Annotation score	3

External links

PDB	RCSB:8jgj, PDBe:8jgj, PDBj:8jgj
PDBsum	8jgj
PubMed	39107281
UniProt	P51791\|CLCN3_MOUSE H(+)/Cl(-) exchange transporter 3 (Gene Name=Clcn3)

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