Structure of PDB 8j9g Chain A Binding Site BS02

Receptor Information
>8j9g Chain A (length=448) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPAQFHDQ
LKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTA
AYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGD
GTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFI
HARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGN
AYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDI
LALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8j9g Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R72 K247 I248 K287 E327 Y328 R362 T363 R364 A402 F403 S431 T432 M435
Binding residue
(residue number reindexed from 1)
R72 K188 I189 K228 E268 Y269 R303 T304 R305 A343 F344 S372 T373 M376
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8j9g, PDBe:8j9g, PDBj:8j9g
PDBsum8j9g
PubMed37932527
UniProtA0A1I7NFD7

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