Structure of PDB 8j8h Chain A Binding Site BS02

Receptor Information
>8j8h Chain A (length=452) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGSMKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQ
KGLQIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEIT
DEEIRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEI
FHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWT
ISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFL
DNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPK
EVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPI
MRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQV
LKDILALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKY
YI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8j8h Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R72 R243 K247 K286 K287 Y328 T363 R364 F403 T432 L433 M435
Binding residue
(residue number reindexed from 1)		R75 R188 K192 K231 K232 Y273 T308 R309 F348 T377 L378 M380
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8j8h, PDBe:8j8h, PDBj:8j8h
PDBsum8j8h
PubMed37932527
UniProtA0A1I7NFD7

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