Structure of PDB 8j62 Chain A Binding Site BS02

Receptor Information
>8j62 Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GHMDPDTFSYNFNNRPILSRRNTVWLCYEVERLDNGTWVKMDQHRGQVYS
ELKYHPEMRFLSLVSKWKLHRDQEYEVTWYISWSPCTKCARDMATFLQEN
THVTLTIFVARLYYFWDPDYQEALRSLAQAGATIKIMNYDEFQHCWSKFV
YSQGAPFQPWDGLDEYSQALSGMLGEILRH
Ligand information
Receptor-Ligand Complex Structure
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PDB8j62 Structural insights into RNA bridging between HIV-1 Vif and antiviral factor APOBEC3G.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K64 K66
Binding residue
(residue number reindexed from 1)		K66 K68
Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:8j62, PDBe:8j62, PDBj:8j62
PDBsum8j62
PubMed37419875
UniProtQ9HC16|ABC3G_HUMAN DNA dC->dU-editing enzyme APOBEC-3G (Gene Name=APOBEC3G)

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