Structure of PDB 8j1j Chain A Binding Site BS02

Receptor Information
>8j1j Chain A (length=424) Species: 1765684 (Sulfoacidibacillus thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSMIKVYRYEIVKPLDLDWKEFGTILRQLQQETRFALNKATQLAWEWMGY
SSDYKDNHGEYPKSKDILGYTNVHGYAYHTIKTKAYRLNSGNLSQTIKRA
TDRFKAYQKEILRGDMSIPSYKRDIPLDLIKENISVNRMNHGDYIASLSL
LSNPAKQEMNVKRKISVIIIVRGAGKTIMDRILSGEYQVHASQIIHDDRK
NKWYLNISYDFEPQTRVLDLNKIMGIDLGVAVAAYMAFQHTPARYKLEGG
EIENFRRQVESRRISMLRQGKYAGGARGGHGRDKRIKPIEQLRDKIANFR
DTTNHRYSRYIVDMAIKMGCGTIQMEDLTNIRDIGSRFLQNWTYYDLQQK
IIYKAEEAGIKVIKIDPQYTSQRCSECGNIDSGNRIGQAIFKCRACGYEA
NADYNAARNIAIPNIDKIIAESIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8j1j Minimal and most efficient genome editing Cas enzyme
Resolution2.91 Å
Binding residue
(original residue number in PDB)
Y68 T69 H72 Y76 K80 N87 S88 S92 S147 S150 N151
Binding residue
(residue number reindexed from 1)
Y70 T71 H74 Y78 K82 N89 S90 S94 S149 S152 N153
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8j1j, PDBe:8j1j, PDBj:8j1j
PDBsum8j1j
PubMed
UniProtA0A2U3D0N8|CS12F_SULT2 CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f1)

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