Structure of PDB 8it1 Chain A Binding Site BS02

Receptor Information
>8it1 Chain A (length=465) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKY
CRPNSVLYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPI
RDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSK
NPQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQA
LESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSK
PLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIF
IEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTA
STEIKTPPLAFKYYI
Ligand information
>8it1 Chain D (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagguaguagguuguauagu
.....................
Receptor-Ligand Complex Structure
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PDB8it1 Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.41 Å
Binding residue
(original residue number in PDB)		E327 K390 L423 S434 M435 N439
Binding residue
(residue number reindexed from 1)		E285 K348 L381 S392 M393 N397
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8it1, PDBe:8it1, PDBj:8it1
PDBsum8it1
PubMed37783228
UniProtA0A1I7NFD7

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