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Receptor Information

>8i3q Chain A (length=595) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PRPRYREERTLVRKLLPRPGQSKQEFRENVKKLRKAFLQFNADVSGVCQW
AIQFRPRYGKPAEPTETFWKFFLEPETSLPPNDSRSPEFRRLQAFEAAAG
ILDDPAFTNELRDSILAVASRPKTKEAQRLFSRLKDYQPAHRMILAKVAA
EWIESRYRRAHQNWERNYEEWKKEKQEWEQNHPELTPEIREAFNQIFQQL
EVKEKRVRICPAADELYRKWRREYWREPRKPVFRYPSVKRHSIAKIFGEN
YFQADFKNSVVGLRLDSMPAGQYLEFAFAPWPRNYRPQPGETEISSVHLH
FVGTRPRIGFRFRVPHKRSRFDCTQEELDELRSRTFPRKAQDQKFLEAAR
KRLLETFPGNAEQELRLLAVALGTDSARAAFFIGKTFQQAFPLKIVKIEK
LYEQWPNQPRPGLSRDHVGRHLQKMRAQASEIAQKRQELTLQPFDLRGLT
VHTARMIRDWARLNARQIIQLAEENQVDLIVLESLRGFRPPGYENLDQEK
KRRVAFFAHGRIRRKVTEKAVERGMRVVTVPYLASSKVCAECRKKQKDNK
QWEKNKKRGLFKCEGCGSQAQVDENAARVLGRVFWGEIELPTAIP

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

8i3q Chain A Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8i3q Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage.
Resolution	3.1 Å
Binding residue (original residue number in PDB)	C711 C735
Binding residue (residue number reindexed from 1)	C539 C563
Annotation score	4

Enzyme Commision number

	Molecular Function
GO:0003677	DNA binding
GO:0046872	metal ion binding

PDB	RCSB:8i3q, PDBe:8i3q, PDBj:8i3q
PDBsum	8i3q
PubMed	37729124
UniProt	A0A7C2YU39

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Structure of PDB 8i3q Chain A Binding Site BS02