Structure of PDB 8hxy Chain A Binding Site BS02

Receptor Information
>8hxy Chain A (length=102) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDL
RFQSSAVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRG
ER
Ligand information
>8hxy Chain J (length=170) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aatacatgcacaggatgtatatatctgacacgtgcctggagactagggag
taatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgtttaa
gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
ctccagtctagaactggcag
Receptor-Ligand Complex Structure
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PDB8hxy Structure of histone deacetylase complex Rpd3S bound to nucleosome
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K37 R40 Y41 R42 T45 R63 R83 F84 Q85 R116 V117 T118
Binding residue
(residue number reindexed from 1)
K5 R8 Y9 R10 T13 R31 R51 F52 Q53 R84 V85 T86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8hxy, PDBe:8hxy, PDBj:8hxy
PDBsum8hxy
PubMed37798513
UniProtP84233|H32_XENLA Histone H3.2

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