Structure of PDB 8hme Chain A Binding Site BS02

Receptor Information
>8hme Chain A (length=532) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSDASRKDLLIQRAEWEVKQGNWKKGGELYIQAEVYKKAIEVYVTNNFSE
GIVEVCRNADAETQRKEIEQCAAYFKKAKLHQYTKEAYLKLQDNKALLQL
NIDLEKWDEAMTLAKAHPEFMEIVKLPYANWLAKQDRYEESLKAYRKIGK
HDMATKMLYNLSQNAVFEKRFSDAALFTWMIATEHLGLIRNMKAPTPEDI
ENLMKFYQYRDDAEIYFAYSKVQSFVDEPFLPLSGHAYMLNIFNAARFAI
NKLGNRQLYGVQHSYLYYSLGKVSKQLEGYKTARICYEKLASYKIPTEWS
EEIELSTLLIRSKPYSDQESLLPICNRCYNQNPALTEGNRCSSCMHQFQN
CFISFENLPLVEFKLDPKITHKRFIELINSDKSKTQPNKKKKKANDGWQE
SHQGDQQVLTFNNSPQKGGNDNESSPFLDKLNEVFEIQQTTQEYIPVTLD
ENIVSSLSIDEVYWVDYTKYCYTAEIKYYKSMLTDIPLKNCQECGTFYIL
DEYEFEISKTQKCPFCRSVDERAGPQKDVFDF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8hme Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8hme Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		C1210 C1213 C1235
Binding residue
(residue number reindexed from 1)		C491 C494 C516
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0035721 intraciliary retrograde transport
GO:0060271 cilium assembly
GO:0061512 protein localization to cilium
GO:1905515 non-motile cilium assembly
Cellular Component
GO:0030991 intraciliary transport particle A
GO:0097730 non-motile cilium

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Biological Process
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Cellular Component
External links
PDB RCSB:8hme, PDBe:8hme, PDBj:8hme
PDBsum8hme
PubMed36932088
UniProtQ244W3

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