Structure of PDB 8hbm Chain A Binding Site BS02

Receptor Information
>8hbm Chain A (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEER
Ligand information
Receptor-Ligand Complex Structure
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PDB8hbm Structural basis of the farnesoid X receptor/retinoid X receptor heterodimer on inverted repeat DNA
Resolution3.3 Å
Binding residue
(original residue number in PDB)		E153 G154 F158 R161 R184 N185 Q188 R191
Binding residue
(residue number reindexed from 1)		E23 G24 F28 R31 R54 N55 Q58 R61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8hbm, PDBe:8hbm, PDBj:8hbm
PDBsum8hbm
PubMed37287811
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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