Structure of PDB 8gna Chain A Binding Site BS02

Receptor Information
>8gna Chain A (length=1188) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGRTAGKSF
ITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDKKPSFLRKRHTL
QWQANICDKEEACPFCILLGRFDNAGKERNKDYDIHFSNFDLDDLRLVDI
ASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRITLRNEHAKKLLLA
SLGFVDKLCGALCRIEVIHNDELRKQAEVIVEAFKQNDKLEKIRILADAI
RTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGTALRTKLKELWQSN
KDIGWRKFTEMLGSNLYLIYKKETSDLFIPVTPPEGIETKEWIIVGRLKA
ATPFYFGVQQPSDSIPGEHASFNILLDKENRYRIPRSALRGALRRDLRTA
FGSGCNVSLGGQILCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPG
TATVEDGSLFDIEVGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKN
GMAWLGGLDSTGKGRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLE
MLPDGLIPYKFFEERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISA
LTEPGNRAAIAYKKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTG
DLGKEDHEDCTCDMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHV
AIDRFTGGALDKAKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITT
ALSDIRDGLYPLGSKGGVGYGWVAGISIDDNVPDDFKEMIINNDYVHPGH
QSPKQDNIYYPHYFLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLT
PLIIPDTSDENGLKLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFE
ALTKSCFAIFGEDSTLKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYK
GRVKFGFAKYENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIP
GRKFYLHHNGWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVRFEN
LREWELGLLLQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVP
QSDIREYINKGYQKLIEWLPQWHVIPHIDKLYKLLWVPFLLEPDVRYPVL
NEESKGDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8gna Target RNA-guided protease activity in type III-E CRISPR-Cas system.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		A188 K189 R294 I295 K320 E322 R323 H328 Y367 K371 F458 D542 G543 S544 L545 F546 E761 D801 K802 K804 F805 L1459 S1461 R1505 L1648
Binding residue
(residue number reindexed from 1)		A166 K167 R244 I245 K270 E272 R273 H278 Y317 K321 F372 D456 G457 S458 L459 F460 E671 D711 K712 K714 F715 L983 S985 R1029 L1150
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:8gna, PDBe:8gna, PDBj:8gna
PDBsum8gna
PubMed36484100
UniProtA0A0B0EGF3

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