Structure of PDB 8g8g Chain A Binding Site BS02

Receptor Information
>8g8g Chain A (length=111) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVRE
IAQDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKD
IQLARRIRGER
Ligand information
>8g8g Chain J (length=174) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gttaagtggtattaacatatcctcagtggtgagtattaacatggaactta
ctccaacaatacagatgctgaataaatgtagtctaagtgaagaaagaagg
aaaggtgggagctgccatcactcagaattgtccagcagggattgtgcaag
cttgtgaataaagacacatacttc
Receptor-Ligand Complex Structure
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PDB8g8g Histone modifications regulate pioneer transcription factor cooperativity.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		R26 R40 Y41 P43 G44 V46 R49 R63 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)		R3 R17 Y18 P20 G21 V23 R26 R40 K41 L42 P43 R46 R60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:8g8g, PDBe:8g8g, PDBj:8g8g
PDBsum8g8g
PubMed37225990
UniProtP84233|H32_XENLA Histone H3.2

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