Structure of PDB 8g86 Chain A Binding Site BS02

Receptor Information
>8g86 Chain A (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8g86 Chain J (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtgactatgtgcgcatgcatgtgcatgtgtgtgcatatacgtgtgtgca
tgcatgtgcatatatgtgtgcacgtgtgtgtgcatgtgtgtgtatgtgta
tatattaacctgtgtgcattgtgtgcatatattagcatgtgtgca
Receptor-Ligand Complex Structure
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PDB8g86 Histone modifications regulate pioneer transcription factor cooperativity.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		R40 Y41 P43 G44 V46 R49 R63 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)		R3 Y4 P6 G7 V9 R12 R26 K27 L28 P29 R32 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8g86, PDBe:8g86, PDBj:8g86
PDBsum8g86
PubMed37225990
UniProtP84233|H32_XENLA Histone H3.2

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