Structure of PDB 8g6r Chain A Binding Site BS02

Receptor Information
>8g6r Chain A (length=899) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DMAYLNRVRGSSAARLEPCNGTDTQHVYRAFDIYNKDVACLGKFLKVNCV
RLKNLDKHDAFYVVKRCTKSAMEHEQSIYSRLEKCGAVAEHDFFTWKDGR
AIYGNVCRKDLTEYTMMDLCYALRNFDENNCDVLKSILIKVGACEESYFN
NKVWFDPVENEDIHRVYALLGTIVSRAMLKCVKFCDAMVEQGIVGVVTLD
NQDLNGDFYDFGDFTCSIKGMGIPICTSYYSYMMPVMGMTNCLASECFVK
SDIFGEDFKSYDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCI
VHCANFNTLFSTTIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNN
DLNSINELLQFCSDPALLIASSPALVDQRTVCFSVAALGTGMTNQTVKPG
HFNKEFYDFLLEQGFFSEGSELTLKHFFFAQKGDAAVKDFDYYRYNRPTV
LDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLNKSAGYPLNKFGKAG
LYYESLSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGGVSLL
STMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPC
LMGWDYPKCDRALPNMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVL
TEVVYSNGGFYLKPGGTTSGDATTAYANSVFNIFQAVSANVNKLLSVDSN
VCHNLEVKQLQRKLYECCYRSTTVDDQFVVEYYGYLRKHFSMMILSDDGV
VCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINKGPHEFC
SQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLA
IDAYPLSKHENPEYKKVFYVLLDWVKHLYKTLTAKFWDESFYANMYEKS
Ligand information
>8g6r Chain J (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gguugugauuuuaauagcuu
....................
Receptor-Ligand Complex Structure
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PDB8g6r An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		N494 K495 S496 K540 Y541 V552 R564 T587 F589 Y684 F910 F915 M919
Binding residue
(residue number reindexed from 1)		N486 K487 S488 K532 Y533 V544 R556 T579 F581 Y676 F886 F891 M895
Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005524 ATP binding
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8g6r, PDBe:8g6r, PDBj:8g6r
PDBsum8g6r
PubMed36993498
UniProtA0A0U2C263

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