Structure of PDB 8g2p Chain A Binding Site BS02
Receptor Information
>8g2p Chain A (length=347) Species:
10090
(Mus musculus) [
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DKLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNT
GSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFGNPLSHFL
EGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPE
EISVNIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKQG
ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKK
EFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECL
RTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFDKL
Ligand information
>8g2p Chain F (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
8g2p
Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and GTP
Resolution
2.521 Å
Binding residue
(original residue number in PDB)
R161 S165 A168 N196 Y200 Y201 K372
Binding residue
(residue number reindexed from 1)
R14 S18 A21 N49 Y53 Y54 K212
External links
PDB
RCSB:8g2p
,
PDBe:8g2p
,
PDBj:8g2p
PDBsum
8g2p
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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