Structure of PDB 8f6i Chain A Binding Site BS02

Receptor Information
>8f6i Chain A (length=274) Species: 211586 (Shewanella oneidensis MR-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FWVKLASRASVATALTLITIKLLAWLYSGSASMLASLTDSFADTLASIIN
FIAIRYAIVGKAEPLAALAQSAFIMGSAFLLLFYGGERLLNPSPVENATL
GVVVSVVAIVLTLALVLLQKRALAATNSTVVEADSLHYKSDLFLNAAVLL
ALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQALLDRELDEDTRQ
RIKLIAKEDPRVLGLHDLRTRQAGKTVFIQFHLELDGNLSLNEAHSITDT
TGLRVKAAFEDAEVIIHQDPVQVE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8f6i Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8f6i Characterization of individual Zn2+ binding sites of YiiP
Resolution4.03 Å
Binding residue
(original residue number in PDB)		H234 H250 D287
Binding residue
(residue number reindexed from 1)		H216 H232 D269
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015086 cadmium ion transmembrane transporter activity
GO:0015093 ferrous iron transmembrane transporter activity
GO:0015341 zinc efflux active transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0006826 iron ion transport
GO:0006829 zinc ion transport
GO:0006882 intracellular zinc ion homeostasis
GO:0034220 monoatomic ion transmembrane transport
GO:0034755 iron ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070574 cadmium ion transmembrane transport
GO:0071577 zinc ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8f6i, PDBe:8f6i, PDBj:8f6i
PDBsum8f6i
PubMed37906094
UniProtQ8E919|FIEF_SHEON Cation-efflux pump FieF (Gene Name=fieF)

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