Structure of PDB 8exx Chain A Binding Site BS02

Receptor Information
>8exx Chain A (length=1088) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGG
DERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHA
YGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNK
EEVDRHLQDLCERMAAALRESPGASFRGISADHFEAEVVERTDVYYYETR
PALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPGFVTFG
WYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSDLPAYKL
MCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHVLLFSL
GSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGPEFVTG
YNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHFQKRSK
IKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRDIPAYY
ATGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINITRTIY
DGQQIRVFTCLLRLADQKGFILPDTQGRFRGAGGEAGRHVGYQGARVLDP
TSGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLE
IEVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLD
KQQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHA
RWAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTA
MGDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKG
VDLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLP
EGLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTV
YYKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLARKLLVSELAEDPA
YAIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWH
PPDDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8exx Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		H508 Q510 K511 K514 G616 Q617 R642 V694 G695 Y696 Q697 G698 V701 N815 V823 G826 L827 K938 R1048 L1138 V1139 S1140 K1174
Binding residue
(residue number reindexed from 1)		H444 Q446 K447 K450 G552 Q553 R578 V590 G591 Y592 Q593 G594 V597 N711 V719 G722 L723 K834 R944 L991 V992 S993 K1027
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