Structure of PDB 8epx Chain A Binding Site BS02

Receptor Information

>8epx Chain A (length=492) Species: 2070761 (Paucibacter aquatile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NAEADFAASEVARMLVADPGLCYDAASLPASISASASYEPSAAGWPKADG
LVSVLEGGTSTQRAIALEYKRPQEGIHGLLTAIGQAHGYLHKGYSGAAIV
IPGRYSSHPTPAEYVRDVLNAISGSRAIAVFSYSPPDTTSPTPFAGRIQC
VRPLVFPKTQWVHMREGSTTRDAFFRFLQVAKRLSADPTAPRPTLRSELV
AAIGRLAPGRDPIEYITNTADNKFLTKVWQFFWLEWLATPAVLTPWKLEA
GVYSAPGARTRILREDGTDFSQLWEGRVNSLKETIAGMLNRGEISEAQGW
EAFVGGISATGGGQDKQGVRARAHSYREDIDSALAQLRWIEDDGLPTDQG
YRFMTICERYGGANSRAAIDYMGATLIQTGRYASFLHYINRLSERKFAEN
PLAYTKPGPGGMPVFTEESYWEYLQDLETKLTDELRVMRKVSGRARPRVR
TTFQVELTLLRNYGFVSSTRHRLGVGIPIDWEQVVQALNVDL

Ligand information

>8epx Chain G (length=16) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ggcgcaggtgggaaga

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8epx Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI.
Resolution	3.15 Å
Binding residue (original residue number in PDB)	T177 H181 R183 R295 V296 Q332 H342 S343 E346 Q354 K458 V459 R462 R464 R466 V467 R468
Binding residue (residue number reindexed from 1)	T159 H163 R165 R277 V278 Q314 H324 S325 E328 Q336 K440 V441 R444 R446 R448 V449 R450

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8epx, PDBe:8epx, PDBj:8epx
PDBsum	8epx
PubMed	36987874
UniProt	A0A2N8KYF9

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