Structure of PDB 8eb2 Chain A Binding Site BS02
Receptor Information
>8eb2 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>8eb2 Chain F (length=9) Species:
9606
(Homo sapiens) [
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SLLMWITQV
Receptor-Ligand Complex Structure
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PDB
8eb2
HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
H191 D196 S251 E254 W274 E275
Binding residue
(residue number reindexed from 1)
H191 D196 S251 E254 W274 E275
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8eb2
,
PDBe:8eb2
,
PDBj:8eb2
PDBsum
8eb2
PubMed
36381658
UniProt
A0A140T9X5
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