Structure of PDB 8e7f Chain A Binding Site BS02

Receptor Information
>8e7f Chain A (length=614) Species: 615 (Serratia marcescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YQDPGRLGAPDSWKTAEFNRQWGLEAISAEFAYARGYTGKGITIGVIDNA
ILSHSEFSGKLTRLDNGSYNFSYDKQDNMSFGDHGTHVAGIAAAKRDGAG
MHGVAFDADIIGTKLNDYGNRNGREELIQSAARVINNSWGIAPDIRRDAK
GDIIWLPNGRPDYVAFVKSEVIAEMMRSKSSVEWGSEQPVPTGGHSAMST
LLRAARHGKLIVFSAGNYNNYNIPEAQKSLPYAFPDVLNNYLIVTNLSDE
NQLSVSSTSCGQTASYCVSAPGSDIYSTVGRLESNTGGAVNREAYNKGEL
SLNPGYGNKSGTSMAAPHVTGVAAVLMQRFPYMSADQISAVIKTTATDLG
VAGIDNLFGWGRVNLRDAINGPKMFITKEDIPQEYYVPGSYSEKQFVVNI
PGLGNIVEPGTPVERRCTSSECSFDSWSNDISGHGGLTKTGAGTLALLGN
NTYRGDTWVKQGVLAIDGSVASNVYIENSGTLSGEGTVGAFRAARSGSVA
PGNGIGTLHVLHDAIFDRGSQYNVEVADNGRSDKIAARRAFLNGGSVNVS
LERSQNLLSQNEAQSLLGNKYTILTTTDGVTGRFENANPSYPFVKVALDY
RGNDVGLGITRTDA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8e7f Chain A Residue 712 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8e7f Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E45 E84 K123 D125 A127 M129
Binding residue
(residue number reindexed from 1)		E17 E56 K95 D97 A99 M101
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8e7f, PDBe:8e7f, PDBj:8e7f
PDBsum8e7f
PubMed36859523
UniProtP09489|PRTS_SERMA Extracellular serine protease

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