Structure of PDB 8e3e Chain A Binding Site BS02
Receptor Information
>8e3e Chain A (length=111) Species:
9606
(Homo sapiens) [
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FQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLKVHMR
KHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDH
LHRHLKKDGCN
Ligand information
>8e3e Chain Y (length=21) [
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ggtaaaagacccctccccaaa
Receptor-Ligand Complex Structure
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PDB
8e3e
Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia.
Resolution
2.99 Å
Binding residue
(original residue number in PDB)
K396 Q422 Y438 K454 S478 D479 H482
Binding residue
(residue number reindexed from 1)
K16 Q42 Y58 K74 S98 D99 H102
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8e3e
,
PDBe:8e3e
,
PDBj:8e3e
PDBsum
8e3e
PubMed
36626981
UniProt
O95365
|ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (Gene Name=ZBTB7A)
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