Structure of PDB 8dzj Chain A Binding Site BS02

Receptor Information
>8dzj Chain A (length=416) Species: 1765684 (Sulfoacidibacillus thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PMIKVYRYEIVKPLDLDWKEFGTILRQLQQETRFALNKATQLAWEWMGFS
SDYKDNHGEYPKSKDILGYTNVHGYAYHTIKTKAYRLNSGNLSQTIKRAT
DRFKAYQKEILRGDMSIPSYKRDIPLDLIKENISVNRMNHGDYIASLSLL
SNPAKQEMNVKRKISVIIIVRGAGKTIMDRILSGEYQVSASQIIHDDRKN
KWYLNISYDFEPNKIMGIALGVAVAVYMAFQHTPARYKLEGGEIENFRRQ
VESRRISMLRQGKYAGGARGGHGRDKRIKPIEQLRDKIANFRDTTNHRYS
RYIVDMAIKEGCGTIQMEDLTNIRDIGSRFLQNWTYYDLQQKIIYKAEEA
GIKVIKIDPQYTSQRCSECGNIDSGNRIGQAIFKCRACGYEANADYNAAR
NIAIPNIDKIIAESIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8dzj An engineered hypercompact CRISPR-Cas12f system with boosted gene-editing activity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		Y68 T69 H72 Y76 K80 S88 S92 S147 S150 N151 R161
Binding residue
(residue number reindexed from 1)		Y69 T70 H73 Y77 K81 S89 S93 S148 S151 N152 R162
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:8dzj, PDBe:8dzj, PDBj:8dzj
PDBsum8dzj
PubMed37400536
UniProtA0A2U3D0N8|CS12F_SULT2 CRISPR-associated endodeoxyribonuclease Cas12f1 (Gene Name=cas12f1)

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