Structure of PDB 8dwm Chain A Binding Site BS02
Receptor Information
>8dwm Chain A (length=248) Species:
11801
(Moloney murine leukemia virus) [
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TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKTNDYRPVQDLREVNKRVEDIH
PTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPS
GQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAA
TSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
Ligand information
>8dwm Chain G (length=8) [
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taactaag
Receptor-Ligand Complex Structure
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PDB
8dwm
Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Resolution
2.99 Å
Binding residue
(original residue number in PDB)
L99 D114 R116 G191
Binding residue
(residue number reindexed from 1)
L76 D88 R90 G161
Enzymatic activity
Enzyme Commision number
2.7.7.-
2.7.7.49
: RNA-directed DNA polymerase.
2.7.7.7
: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4
: ribonuclease H.
3.4.23.-
External links
PDB
RCSB:8dwm
,
PDBe:8dwm
,
PDBj:8dwm
PDBsum
8dwm
PubMed
36516684
UniProt
P03355
|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)
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