Structure of PDB 8dw1 Chain A Binding Site BS02

Receptor Information
>8dw1 Chain A (length=242) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVP
NPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRSGQLTWT
RLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAATSELDC
QQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8dw1 Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
Resolution1.849 Å
Binding residue
(original residue number in PDB)
L99 D114 L115 R116 G191
Binding residue
(residue number reindexed from 1)
L76 D84 L85 R86 G155
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
External links
PDB RCSB:8dw1, PDBe:8dw1, PDBj:8dw1
PDBsum8dw1
PubMed36516684
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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