Structure of PDB 8df9 Chain A Binding Site BS02

Receptor Information
>8df9 Chain A (length=781) Species: 2320 (Methanopyrus kandleri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALVYDAEFVGSEREFEEERETFLKGVKAYDGVLATRYLMERSSSAKNDEE
LLELHQNFILLTGSYACSIDPTEDRYQNVIVRGVNFDERVQRLSTGGSPA
RYAIVYRRGWRAIAKALDIDEEDVPAIEVRAVKRNPLQPALYRILVRYGR
VDLMPVTVDEVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHD
EIARRLGLSVSEVEGEKDPESSGIYSLWSRVVVNIEYDERTAKRHVKRRD
RLLEELYEHLEELSERYLRHPLTRRWIVEHKRDIMRRYLEQRIVECALKL
QDRYGIREDVALCLARAFDGSISMIATTPYRTLKDVCPDLTLEEAKSVNR
TLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRLSEEA
YRAAVEIQLAELTKKEGVGRKTAERLLRAFGNPERVKQLAREFEIEKLAS
VEGVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEE
LREDGLTDAQIRELKGLKTLESIVGDLEKADELKRKYGSASAVRRLPVEE
LRELGFSDDEIAEIKGIPKKLREAFDLETAAELYERYGSLKEIGRRLSYD
DLLELGATPKAAAEIKERSEEEWKEWLERKVGEGRARRLIEYFGSAGEVG
KLVENAEVSKLLEVPGIGDEAVARLVPGYKTLRDAGLTPAEAERVLKRYG
SVSKVQEGATPDELRELGLGDAKIARILGLRSLVNARLDVDTAYELARRY
GSVSAVRAAPVAELRELGLSDRAIARIAGIP
Ligand information
Receptor-Ligand Complex Structure
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PDB8df9 Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		S469 Y491 P569 K570 L591 G751 K753 T754 S776 R830
Binding residue
(residue number reindexed from 1)		S468 Y490 P568 K569 L590 G678 K680 T681 S703 R757
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8df9, PDBe:8df9, PDBj:8df9
PDBsum8df9
PubMed35969036
UniProtQ977W1

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