Structure of PDB 8d2o Chain A Binding Site BS02

Receptor Information
>8d2o Chain A (length=749) Species: 351607 (Acidothermus cellulolyticus 11B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTVPVTWRLGVDVGERSIGLAAVSYEEDKPKEILAAVSWIHDGGVGDERS
GASRLALRGMARRARRLRRFRRARLRDLDMLLSELGWTPLPDKNVSPVDA
WLARKRLAEEYVVDETERRRLLGYAVSHMARHRGWRNPWTTIKDLKNLPQ
PSDSWERTRESLEARYSVSLEPGTVGQWAGYLLQRAPGIRLNPTQQSLSN
ATAFETRLRQEDVLWELRCIADVQGLPEDVVSNVIDAVFCQKRPSVPAER
IRPPLPALHEATGHPVVDRNLAILRKFLSSATMRWGPPQSIVVELARGAS
ESESTGYAAVALRDRLLSYGEKNGVAQVAVFRGGVTAEARRWLDISIERL
FSRVAIFAQSTSTKRLDRRHHAVDAVVLTTLTPGVAKTLADARSRRVSAE
FWRRPSTEEPQSPAYRQWKESCSGLGDLLISTAARDSIAVAAPLRLRPTG
ALHEETLRAFSEHTVGAAWKGAELRRIVEPEVYAAFLALTDPGGRFLKVS
PSEDVLPADENRHIVLSDRVLGPRDRVKLFPDDRGSIRVRGGAAYIASFH
HARVFRWGSSHSPSFALLRVSLADLAVAGLLRDGVDVFTAELPPWTPAWR
YASIALVKAVESGDAKQVGWLVPGDELDFGPEGVTTAAGDLSMFLKYFPE
RHWVVTGFEDDKRINLKPAFLSAEQAEVLRTERSDRPDTLTEAGEILAQF
FPRCWRATVAKVLCHPGLTVIRRTALGQPRWRRGHLPYSWRPWSADPWS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d2o Coupled catalytic states and the role of metal coordination in Cas9
Resolution2.66 Å
Binding residue
(original residue number in PDB)		R55 Q202 E839 E840 T841 R843 D1025 R1048 R1088 R1091
Binding residue
(residue number reindexed from 1)		R49 Q196 E454 E455 T456 R458 D640 R663 R703 R706
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d2o, PDBe:8d2o, PDBj:8d2o
PDBsum8d2o
PubMed38348449
UniProtA0LWB3

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